Walker was not only a trailblazer in the medical field; she was also a relentless visionary.

Or

Walker was not only a trailblazer in the medical field, she was also a relentless visionary.

If I saw this appear on an actual test, I’d go with the first one. Technically, you’ve got independent clauses (i.e. complete thoughts) on both sides of the punctuation mark in question, so you want a semicolon.

However, I very much doubt that you’d see this on a real test. That’s because not only __ is usually followed by but also __. For example, “Walker was not only a trailblazer in the medical field, but also a relentless visionary.” For this reason, the not only construction to my ear really calls out for a comma, and a but also, making both options above feel kinda icky.

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